Main
Qiqi Xie
Bioinformatics Scientist. Data scientist. Biologist. Master of Medicine.
I received the B.S. degree in Bachelor of Medicine from Nanchang University, City, China, in 2015, and the M.S. degree in Clinical Surgery from Lanzhou University, City, China, in 2019, and the Ph.D. degree in Oncology from Lanzhou University, China, in 2023.
I am currently a Senior Postdoctoral Research Associate at Indiana University Bloomington, focusing on cancer stem cells, NK and CAR NK immunotherapy.
Fluent in Bioinformatics, NGS analysis, scRNA-seq, and machine learning.
Education
Research Associate
Indiana University Bloomington
Bloomington, IN 47405
to date - 2023
- Senior postdoctoral fellow
Ph.D. in Oncology
Lanzhou University
Gansu, CN
2022 - 2019
- SUV39H1 Maintains Cancer Stem Cells in Glioblastoma
Master of Orthopedics
Lanzhou University
Gansu, CN
2019 - 2016
- Mechanism of TRPM2-GSK3B Signaling Pathway in Diabetic Osteoporosis
Diploma of Clinical Medicine
Nanchang University
Jiangxi, CN
2015 - 2010
Certificate
Outstanding Graduates
N/A
Lanzhou University
2018
National Scholarships
N/A
Lanzhou University
The First-Prize Scholarship
N/A
Lanzhou University
The Third-Prize Scholarship
N/A
Lanzhou University
2016
The Third-Prize Scholarship
N/A
Nanchang University
2014
The Second-Prize Scholarship
N/A
Nanchang University
2012
National College English Competition Encouragement Award
N/A
Nanchang University
2011
Grants
Qinghai Provincial Breast Center Key Specialty Construction
Participation
N/A
2023 - 2022
Popularization and application of early diagnosis and treatment technology for breast cancer in Qinghai Province
Participation
N/A
2022 - 2021
Study on the mechanism of single cell sequencing in bone metastasis of Breast Cancer
Participation
N/A
2021 - 2020
Pain mechanism and treatment of spinal diseases
Participation
N/A
2020 - 2019
The mechanism of exosome microRNAs in osteoporosis
Participation
N/A
Mechanism of TRPM2-GSK3B ta Signaling Pathway in Diabetic Osteoporosis
Participation
N/A
2019 - 2018
Endogenous cannabinoids regulate astrocyte-mediated pain: the MAPK-Glu-Gln shuttle pathway
Participation
N/A
2018 - 2017
Publications
Exploring GZMK as a prognostic marker and predictor of immunotherapy response in breast cancer: unveiling novel insights into treatment outcomes
J Cancer Res Clin Oncol
N/A
2024
- Zitao Li, Qiqi Xie, Fuxing Zhao, Xinfa Huo, Dengfeng Ren, Zhilin Liu, Xiaofeng Zhou, Guoshuang Shen, Jiuda Zhao
- SCI, IF=2.7, JCR Q3
The correlation between systemic inflammatory markers and efficiency for advanced gastric cancer patients treated with ICIs combined with chemotherapy
Immunology
N/A
- Dong Q, Zhao F, Li Y, Shen G, Dong Q, Ren D, Wang M, Zhao Y, Liu Z, Ma J, Xie Q, Liu Z, Li Z, Gao L, Zhao J
- SCI, IF=4.9, JCR Q2
Correlation between mismatch repair and survival of patients with gastric cancer after 5-FU-based adjuvant chemotherapy
J Gastroenterol
N/A
2023
- Zhao F, Li E, Shen G, Dong Q, Ren D, Wang M, Zhao Y, Liu Z, Ma J, Xie Q, Liu Z, Li Z, Gao L, Zhao J
- SCI, IF=6.772, JCR Q1
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration
Apoptosis
N/A
2022
- Wu ZL, Chen YJ, Zhang GZ, Xie QQ, Wang KP, Yang X, Liu TC, Wang ZQ, Zhao GH, Zhang HH
- SCI, IF=5.561, JCR Q2
Role of the Wnt pathway in the formation, development, and degeneration of intervertebral discs
Pathol Res Pract
N/A
- Zuo-Long Wu, Qiqi Xie*, Tai-Cong Liu, Xing Yang, Guang-Zhi Zhang, Hai-Hong Zhang
- SCI, IF=3.250, JCR Q4
- Co-first_authors
A four-methylated LncRNA signature predicts survival of osteosarcoma patients based on machine learning
Genomics
N/A
- Yajun Deng, Wenhua Yuan, Enhui Ren, Guangzhi Zhang, Zuolong Wu, Qiqi Xie*
- SCI, IF=5.732, JCR Q3
- Corresponding_author
Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis
Mediators of Inflammation
N/A
- Yajun Deng, Liang Yang, Qiqi Xie, Fengbiao Yang, Guoqiang Li, Guangzhi Zhang, Shaoping Li, Zuolong Wu, Jing Wang, Xuewen Kang*
- SCI, IF=4.711, JCR Q3
- Co-first_authors
MCM2 and NUSAP1 Are Potential Biomarkers for the Diagnosis and Prognosis of Pancreatic Cancer
BioMed Research International
N/A
- Yajun Deng, Hanyun Ma, Jinyong Hao*, Qiqi Xie*, Ruochen Zhao*
- SCI, IF=3.411, JCR Q3
- Corresponding_author
Decreased expression of NUSAP1 predicts poor overall survival in cervical cancer
Journal of Cancer
N/A
- Qiqi Xie, Wen Ou-yang, Mingwei Zhang, Huimei Wang, Qiuyuan Yue*
- SCI, IF=4.200, JCR Q3
- First_authors
GRB10 and E2F3 as Diagnostic Markers of Osteoarthritis and Their Correlation with Immune Infiltration
Diagnostics
N/A
- Yajun Deng, Enhui Ren, Wenhua Yuan , Guangzhi Zhang, Zuolong Wu, Qiqi Xie*
- SCI, IF=3.701, JCR Q3
- Corresponding_author
Identification of diagnostic markers for major depressive disorder by cross-validation of data from whole blood samples
PeerJ
N/A
2019
- Huimei Wang, Mingwei Zhang, Qiqi Xie, Jin Yu, Yan Qi, Qiuyuan Yue*
- SCI, IF=2.984, JCR Q3
Anterior versus posterior decompression for the treatment of thoracolumbar fractures with spinal cord injury:a Meta-analysis
China journal of orthopaedics and traumatology
N/A
- Enhui Ren, Yajun Deng, Qiqi Xie, Liang Yang, Guangzhi Zhang, Shaoping Li, Zuolong Wu, Jing Wang, Xuewen Kang*
- SCI
Identification of potential diagnostic and therapeutic target genes for lung squamous cell carcinoma
Oncology Letters
N/A
- Nana Zhang, Hong Wang, Qiqi Xie, Hua Cao, Fanqi Wu, Dan Bei Di Wu, Yixin Wan*
- SCI, IF=2.860, JCR Q4
- Co-first_authors
Integrative analyses of genes associated with idiopathic pulmonary fibrosis
Journal of Cellular Biochemistry
N/A
- Huimei Wang, Qiqi Xie, Wen Ou_Yang, Mingwei Zhang*
- SCI, IF=4.423, JCR Q3
Slow skeletal muscle troponin T, titin and myosin light chain 3 are candidate prognostic biomarkers for Ewing’s sarcoma
Oncology Letters
N/A
- Yajun Deng, Qiqi Xie, Guangzhi Zhang, Shaoping Li, Zuolong Wu, Zhanjun Ma, Xuegang He, Yicheng Gao, Yonggang Wang, Xuewen Kang, Jing Wang*
- SCI, IF=2.860, JCR Q4
- Co-first_authors
2-arachidonyl glycerol modulates astrocytic glutamine synthetase via p38 and ERK1/2 pathways
Journal of Neuroinflammation
N/A
- Shenghong Wang, Hua Zhang, Bin Geng, Qiqi Xie, Wenzhou Li, Yajun Deng, Weidong Shi, Yunyan Pan, Xuewen Kang, Jing Wang*
- SCI, IF=8.324, JCR Q2
High-affinity glutamate transporters and chronic pain
Journal of Central South University (Medical Sciences)
N/A
- Zhang H, Wang S, Qiqi Xie, Li W, Shi W, Ma J, Wang J*
- CSCD
- Article in chinese
Advances in application of gemstone energy spectrum CT in skeletal system
Life science Research
N/A
- Xie Q, Li W, Shi W, Deng Y, Ren E, Ma J, Kang X, Wang J*
- CSCD, First_authors
- Article in chinese
Bioinformatics analysis of osteoarthritis expression profile microarray integration
Hua Zhong Ke Ji Da Xue Xue Bao Yi Xue Ban
N/A
- Xie Q, Li W, Shi W, Deng Y, Ren E, Ma J, Kang X, Wang J*
- CSCD, First_authors
- Article in chinese
Effects of diabetes on bone biomechanics in ovariectomized rats
Chinese Journal of Medical Physics
N/A
- Xie Q, Li W, Shi W, Deng Y, Ren E, Ma J, Pan Y, Kang X, Wang J*
- CSCD, First_authors
- Article in chinese
Selection of sites for detecting bone mineral density in diabetic osteoporosis rats by DXA
Chinese Journal of Medical Physics
N/A
- Li W, Xie Q, Ren E, Deng Y, Pan Y, Ma J, Kang X, Wang J*
- CSCD, Co-first_authors
- Article in chinese
The expression and clinical significance of formyl peptide receptor 1 in glioma were analyzed based on bioinformatics
Cancer, aberration, mutation
N/A
- Dong Q, Xie Q, Hu J, Wang M, Yuan G, Pan Y*
- CSCD, Co-first_authors
- Article in chinese
The correlation between quantitative parameters of EDCT and bone biomechanics
Chinese Journal of Medical Physics
N/A
- Dong Q, Xie Q, Zhao R, Huang X, Li W, Zhang Y, Pan Y*
- CSCD, Co-first_authors
- Article in chinese
Preliminary study on the evaluation of biomechanics by EDCT
Chinese Journal of Medical Physics
N/A
- Huang X, Xie Q, Deng Y, Zhao R, Dong Q, Zhou J*
- CSCD, Co-first_authors
- Article in chinese
Progress in the study of skeletal endocrine function
Life science Research
N/A
- Li W, Xie Q, Shi W, Deng Y, Ma Y, Xie J, Kang X, Wang J*
- CSCD, Co-first_authors
- Article in chinese
Conference proceedings
The 3th Academic Conference of Chinese Medical Association on Osteoporosis and Bone Mineral Salt
N/A
Shanxi, CN
2020 - 2018
The 9th International Symposium on Osteoporosis and Bone Mineral Salt Diseases
N/A
Suzhou, CN
The 13th Annual Congress of Chinese Orthopaedic Association
N/A
Xiamen, CN
Professional skills
Wet-lab Experimental
- I am good at Immunohistochemistry, Immunofluorescence, Western Blot, RT-PCR, RNAi, Exosome identification, Open-field Test, Water Maze Test, Forced Swimming Test, Von Frey Hair Test, Cold Hot Plate Test, and Tereotactic Injection.
Experimental instruments
- I can operate the following experimental instruments: micro-drop PCR system, automatic protein expression quantitative system, high-content live cell imaging quantitative analysis system and cell metabolic analyzers.
Software
- I have advanced experience in using Microsoft Office, Illustrator, Photoshop, GraphPad Prism, SPSS, ImageJ, Image-Pro Plus, Cytoscape, Funrich.
Statistics
- I have moderate experience in using R and Python for statistical modeling and data visualization.
Machine learning
- I know how to do machine learning (including deep learning) and have applied some technologies to my projects.
Data analysis
- I have advanced experience in using R and Shell for data preprocessing, data cleaning and data interpretation. RNA-seq, ChIP-seq, ATAC-seq, scRNA-seq, scATAC-seq Analysis. Spatial Transcriptomics.
Disclaimer
Last updated on 2024-07-24.